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“Impossible is just an opinion.” – 

Paulo Coelho


"The ridiculous to the sublime is but a step"

Mutual Respect and Support

For all the talk above about our view of you as a team member, it's important to know that more than anything we believe that whatever your contribution to Expansion, it falls flat if any fail to respect or support fellow team members.  We do not support discrimination of any sort, either during the hiring process or post hire on the basis of race, ethnicity, gender type, beliefs,.. hair style, sock wearing preferences;  It's a long list.  We seek to thrive in and through diversity and are dedicated to maintaining genuine attitudes of respect while doing our best to support and honor your uniqueness.


 – And while we're on it; 



We'd be remiss to mention what underlies the integrity of our work; Being accountable to one another in order to keep the integrity of our work at its highest.  We will go out of our way to ensure our goals stay in alignment with the values of Expansion Therapeutics mentioned above.   

The Silent, (absent) "I" in Team

Bring yourself to this professional outing.  "There is no "I" in Team" does resonate with appropriate equanimity  but we can't abide its limits.  If you're hired to be a part of this endeavor to cure major CNS diseases we'll need you to bring everything you have.  Stand up, say it, do it; and we'll be sure to support you in your vision same as you have come to support ours.   

Culture of Curiosity

If curios is not a state of being, we may not know what else it is.  So whatever else you may encounter as a part of the Expansion Therapeutics team, you can be sure to be both inspired and encouraged to give your curiosity a front-row seat.  Above all be sure not to keep it to yourself.  If you reverse Napoleon's logic, you'll have what we're after here:  

Read our Equal Opportunity statement  

Believe in Yourself

Scientist, Bioinformatics



  • Support and apply leading-edge computational analysis and biological interpretation approaches aligned with key scientific objectives

  • Integrate data across assay platforms and transfer knowledge to impact early drug discovery development programs

  • Apply contemporary methods for data processing, analysis, interpretation, and visualization

  • Contribute to development and implementation of both established and novel NGS data processing protocols for cell lines, tissues, and targets of interest

  • Participate in design and analysis of laboratory experiments; algorithm, platform & vendor performance evaluations; and the development of novel profiling protocols

  • Author scientific reports, and present methods, results, and conclusions to publishable standard

  • Contribute to planning and execution of collaborative projects with leading academic and commercial research groups

  • Develop and utilize pipelines to contribute to target engagement studies across multiple targets

  • Support to mechanism of action and biomarker studies

  • Leverage insights gained from NGS to support drug discovery projects

  • Communicate and report data packages to an interdisciplinary team

  • Prepare reports and presentations for leadership and participate in internal/external meetings


  • Bachelors with a minimum of 5 years’ experience; or a master’s with a minimum of 2 years of experience; or a PhD with a minimum 0 - 1 yrs. related experience within synthetic organic chemistry

  • Proven experience in RNA-Seq analysis is required

  • Knowledge and expertise in programming languages such as Python and R

  • Proven skills in handling and archiving large-scale data in a cloud-based environment

  • Knowledge with next generation sequencing techniques to analyze RNA splicing is strongly preferred

  • Understanding with RNA biology including RNA structure, alternative splicing, translation, and other areas is strongly preferred

  • Experience with RNA structure prediction is a plus


  • Excellent written and oral communication skills.

  • Ability to work independently and collaborate in a multi-disciplinary environment.

  • Critical thinker with a demonstrated ability to effectively collaborate across teams and functional areas.

  • Success-oriented individual with relentless drive towards company and team goals and timelines.

  • Contribute to our company culture, sense of team and collaborative spirit.

  • Must be legally authorized to work in the United States.

Expansion Therapeutics fosters an inclusive company culture that values diverse talent, backgrounds, and experiences. We are proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity, national origin, genetics, disability, age, sexual orientation, veteran status, or any other legally protected categories.

Reporting to the Senior Vice President, Drug Discovery, the Scientist, Bioinformatics will be responsible for the analysis of next generation sequencing data to support mechanism of action and biomarker studies. This is a direct laboratory position based in our Jupiter, Florida research site.

*Title will be commensurate with experience.

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Boston, MA

Jupiter, FL