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Join the Future of RNA Mediated Disease Research

CAREERS

Our mission is a big idea - to provide a cure for those suffering from CNS diseases. 

 

We look at the small details...sequence and structure of RNA.  Important insights that makes our work relevant and of utmost importance.    

Do you have a big vision and laser focus?  You're the person we're looking for to help expand this life-changing work!

CURRENT OPENINGS

In Vivo Research Technician

Reporting to the Senior Scientist I, the candidate will be responsible for performing preclinical-stage in vivo studies. This is a direct laboratory position based in our Jupiter, Florida research site.


*Title will be commensurate with experience.

May 3, 2022

Associate Director / Director Medicinal Chemistry

Reporting to the Senior Vice President, Research, the Associate Director / Director in Medicinal Chemistry will be a key member of our Drug Discovery and Research teams tasked with devising and driving medicinal chemistry strategies across novel drug discovery projects with the goal of advancing through hit-to-lead and lead optimization studies to clinical candidate selection. The successful  candidate will have a proven track record of success in medicinal chemistry with accomplishments resulting in high impact on drug discovery programs and/or delivery of high-quality development candidates. The candidate will work collaboratively within an energetic, matrixed research organization, helping guide teams and communicate the importance of our work to a broad audience. This position will be based in Boston/Cambridge, MA.

May 3, 2022

Scientist, Cell Biology

Reporting to the Director, Research/Site head, the individual will join the research team bring their cellular biology expertise to deliver high quality, decision-driving studies to define pharmacodynamic and pharmacokinetic (PK/PD) relationships. Expansion Therapeutics is looking for an accomplished hands-on cellular biologist who will make significant contributions to the execution of cell-based studies in the area of RNA-mediated diseases. The candidate will be responsible for applying the latest knowledge and techniques in the field. The individual will advance the assigned program and contribute to the identification of a lead or development candidate. The individual will utilize sound knowledge of target identification and validation in a drug discovery context. This is a direct laboratory position based in our Jupiter, Florida research site.


*Title will be commensurate with experience.

Apr 1, 2022

Scientist, Bioinformatics

Reporting to the Senior Vice President, Drug Discovery, the Scientist, Bioinformatics will be responsible for the analysis of next generation sequencing data to support mechanism of action and biomarker studies. This is a direct laboratory position based in our Jupiter, Florida research site.


*Title will be commensurate with experience.

Apr 1, 2022

Scientist, ALS

Expansion Therapeutics is seeking a highly motivated Scientist to join our discovery research team and contribute to the development of new innovative therapies for patients with serious RNA-mediated diseases. The ideal candidate will have a background in biology, chemical biology, or biochemistry or related field. This position will work closely with discovery program teams to evaluate and advance candidates and execute on key experiments to better understand and optimize RNA-targeting small molecules. This is a direct laboratory position based in our Jupiter, Florida research site.


*Title will be commensurate with experience.

Apr 1, 2022

Scientist, Medicinal Chemistry

Reporting to the Senior Vice President, Drug Discovery, the candidate will be responsible for the synthesis and characterization of small molecules that bind RNA. He/She will integrate a broad understanding of synthetic organic chemistry and medicinal chemistry with the goal of developing probe molecules for a pharmacological target of interest. This is a direct laboratory position based in our Jupiter, Florida research site.


*Title will be commensurate with experience.

Apr 1, 2022

Laboratory Operations/Facilities

Reporting to the Director of Research, the Laboratory Operations/Facilities candidate will manage, coordinate, and maintain all laboratory activities for the Jupiter, FL site. He/she will provide superior organizational skills, and positive outgoing personal presence to ensure a safe, functional, well-organized, and vibrant workspace.


*Title will be commensurate with experience.

Apr 1, 2022

Associate Director, Program Management

Reporting to the Senior Vice President, Drug Discovery, the Associate Director, Program Management will be responsible for cross-functionally driving the successful advancement of Expansion Therapeutics programs and platform efforts. The successful candidate will be a dynamic leader and facilitator with a track record of managing programs at the discovery and/or development stage. He/She will coordinate, develop, and direct project strategies, set goals, and facilitate team decision making for the programs. He/She will possess strong attention to detail, the ability to communicate effectively at all levels, and adeptness at facilitating actions and resolving conflicts. A key aspect of this position is the ability to drive programs forward so that they align with the company strategy, commitments, and goals. Must be able to travel domestically (no more than 10%).

Jan 28, 2022

Scientist, Biophysics

Reporting to the Senior Vice President, Research, the Scientist, Biophysics will be key member of our Research group, responsible for the biophysical and mechanistic characterization of small molecules binding to RNA. The Principal Scientist will integrate a broad understanding of biophysics with RNA dynamics, enzymology, and structural biology with the goal of understanding the molecular mechanism of action and corresponding pharmacology of a diverse set of RNA targets. Industry experience in biophysical biology is essential. This is a hands-on laboratory position based in our Jupiter, Florida research site.


*Title will be commensurate with experience.

Jan 24, 2022

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LOCATIONS:

Headquarters

Boston, MA

Research

Jupiter, FL