The Disney Lab
The Disney Lab is focused on developing rational and predictable approaches to design highly selective therapeutics from sequence. One of the major articulations of the utility of genome sequencing efforts has been in advancing patient-specific therapies, yet such developments have been only sparsely reported. The Disney Lab seeks to accomplish this lofty goal by using advancements in annotating RNA structure from sequence and several novel technologies that have been recently developed in their laboratory. Their current focus is on leveraging these technological advances to identify patient-specific therapies targeting orphan diseases that have no known cure or more common disorders to which there is a poor prognosis, such as drug resistant cancers.
Myotonic Dystrophy Foundation
The Myotonic Dystrophy Foundation (MDF) is the world’s largest patient organization focused solely on myotonic dystrophy. MDF’s mission, “Care and a Cure,” is to enhance the quality of life of people living with myotonic dystrophy (DM) and advance research focused on treatments and a cure. MDF provides emotional support, education and resources to affected individuals and their families, and conducts outreach to raise awareness about DM in the medical community and the general population. MDF is committed to advancing DM research and therapies. MDF has launched and manages the Myotonic Dystrophy Family Registry, and supports a robust clinical research network to increase the efficiency of testing new drug candidates.
5AM Ventures is a leading venture capital firm focused on building next-generation life science companies capable of delivering outstanding returns to our investors. 5AM supports companies that are working to solve important healthcare needs via cutting-edge breakthroughs in medicine and science. 5AM portfolio companies spearhead novel approaches to diagnose, prevent and treat a wide range of medical conditions. 5AM’s investment professionals possess strong scientific, medical, operational, legal and finance expertise. 5AM’s team employs a time-tested, hands-on approach to company-building and, in addition to being an early investor, 5AM is often directly involved in setting company strategy, management recruiting, business development and fundraising.
Kleiner Perkins has partnered with some of the most ingenious founders in technology and life sciences, helping them make history with their bold ideas. Through twenty venture funds and four growth funds, Kleiner Perkins has invested $10 billion in hundreds of companies including pioneers such as Amazon, Genentech, and Google. Today, Kleiner Perkins continues to invest in founders and their bold ideas helping them to make history.
Novartis Venture Fund
Novartis Venture Fund is focused on the development of novel therapeutics and platforms. In their investments, NVF looks for unmet need and clinical impact, novel proprietary science and understanding of mechanism, management and board experience and capital efficiency in the program. NVF invests in North America, Europe, Israel and Asia/Pacific with approximately $800 million under management in committed capital and more than 40 portfolio companies. NVF is stage agnostic and engages in seed investments as well as later-stage investments.
Sanofi Ventures is the corporate venture capital arm of Sanofi. Sanofi Ventures has the ability to seed and to lead financings in early-stage companies with innovative ideas and transformative new products and technologies that are of strategic interest to Sanofi. Among these areas are rare diseases, vaccines, potential cures in other core areas of Sanofi’s business footprint, and digital health solutions. In addition to financing, Sanofi Ventures offers its portfolio companies access to Sanofi’s established expertise and capabilities in science, preclinical and clinical development, regulatory, manufacturing, market access, commercialization, and more. Sanofi Ventures seeks to build strong relationships with innovators and entrepreneurs and is fully engaged with management through board positions or advisory committee membership.
The Scripps Research Institute
The Scripps Research Institute (TSRI), one of the world’s largest, private, non-profit research organizations, stands at the forefront of basic biomedical science, a vital segment of medical research that seeks to comprehend the most fundamental processes of life. Over the last decades, the institute has established a lengthy track record of major contributions to the betterment of health and the human condition. Located on campuses in La Jolla, California, and Jupiter, Florida, TSRI has become internationally recognized for its research into immunology, molecular and cellular biology, chemistry, neurosciences, autoimmune diseases, cardiovascular diseases, virology and vaccine development. Particularly significant is the institute’s study of the basic structure and design of biological molecules; in this arena TSRI is among a handful of the world’s leading centers.
RA Capital Management
RA Capital Management (RA Capital®) is a multi-stage investment manager dedicated to evidence-based investing in public and private healthcare and life science companies that are developing drugs, medical devices, and diagnostics. The flexibility of its strategy allows RA Capital® to provide seed funding to startups and to lead private, IPO, and follow-on financings for its portfolio companies, both facilitating the crossover process and allowing management teams to drive value creation with fewer capital concerns from inception through commercialization.
Alexandria Venture Investments
Alexandria Real Estate Equities (NYSE:ARE), an S&P 500® company, is an urban office REIT uniquely focused on collaborative life science and technology campuses. Alexandria has a longstanding and proven track record of developing Class A properties clustered in urban life science and technology campuses that provide its innovative tenants with highly dynamic and collaborative environments that enhance their ability to successfully recruit and retain world-class talent and inspire productivity, efficiency, creativity, and success.